Extensive investigations with respect to toxicology and safety have shown that xanthan gum is a safe food additive. It was cleared by the FDA (the US Food and Drug Administration) in 1969 and is registered in the Code of federal Regulations. In 1980 the EC approved xanthan gum under the number E 415. In 1988 the ADI (acceptable daily intake) of xanthan gum was changed to "not specified" confirming its status as a safe food additive.

The xanthan gum food grade produced by Biopolymer members fully meets the standards and the purity criteria issued in the latest versions of USP/NF (US Pharmacopoeia/National Formulary), EP (European Pharmacopoeia), FCC (Food Chemicals Codex) and the respective EC directive.